Arsenal is level on points with Manchester City with both sides having 19 points with Spurs a point adrift.
The Gunners are unbeaten in 11 matches in all competitions and comfortably won their last game in the Champions league on Wednesday 20th, October, 2016 thrashing Ludogorets 6-0.
Alexis Sanchez was taken off through the second half sparking fears that he could have suffered an injury.
However, the Arsenal manger, Arsene Wenger quelled injury worries concerning the 27-year- old Chilean a head of their game against Middlebrough.
Speaking at his post-match news conference on Wednesday night, Wenger said: “I just wanted to give him a breather. He looks alright physically.”
Middlesbrough travel to Arsenal having not won a game in their last six league matches and are only above the relegation zone on goal difference.
Bournemouth cruised to a massive 6-1 win when they faced Hull City in their last game while Tottenham Hotspur are the only unbeaten side in the Premier League.
David Moyes will look to guide Sunderland who are bottom of the table to their first league win of the season at West Ham, Swansea City play Watford, Stoke travel to Hull and Burnley are at home to Everton.
Sunday 23rdOctober Fixtures
Manchester City will play Southampton at the Eastland while Manchester United manager Jose Mourinho returns to former club Chelsea.
Chelsea will look to carry on from their 3-0 win over faltering Premier League champions Leicester.
Premier League Fixtures:
Arsenal v Middlesbrough
Bournemouth v Tottenham
Burnley v Everton
Hull v Stoke
Leicester v Crystal Palace
Liverpool v West Brom
Swansea v Watford
West Ham v Sunderland
Chelsea v Manchester United
Manchester City v Southampton