Monaco have sacked manager Leonardo Jardim after their woeful start to the season

Jardim’s dismissal news potentially opens the way for Thierry Henry to become the French club’s next boss after their former striker was linked to the vacancy. Former France and Arsenal star Henry 41, began his career at Monaco and helped them win Ligue 1 in 1997.

Portuguese boss Jardim was appointed in 2014 and led the club to the French title in 2017, their first since 2000.

The 44-year-old also guided Monaco to the Champions League semi-finals in 2016-17 and helped develop players such as forward Kylian Mbappe, now at Paris St-Germain, Thomas Lemar, Benjamin Mendy among others.

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The Balkans lead Group D after having won the first two games, but they can lose first place if Nigeria beat Argentina by a landslide. Jorge Sampaoli‘s side, on the other hand, would be finish second if they beat Nigeria and Iceland don’t beat Croatia.

Croatia smashed Argentina by 3-0 to reach Round of last 16

“The best team in Group D is Croatia,” Frenchman Paul Pogba said at the French team’s headquarters outside Moscow.

“They are a great team that were able to beat Argentina.”

Argentina looks to be so weak in this year’s edition

His teammate Corentin Tolisso agreed in the analysis that Croatia are the most dangerous opponent possible.

“Croatia are the best in that group, and we will do everything possible to not finish second,” said the Bayern Munich midfielder.

Tolisso acknowledged that, in case of having to play against Argentina, it will be necessary to pay particular attention to Messi.

France qualified for Round of 16 by beating Peru 1-0

“The Argentines have strong individualities, especially with Messi, who can do anything in a game,” he added.

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Both Pogba and Tolisso highlighted that France are the only one of the big nations that managed to qualify for the second round after the first two matches of the World Cup, and drew attention to the problems that other teams go through as an example of the difficulty that entails.

“The big teams don’t come to party, we come to win, we have quality players, a good squad, winning is possible, but it will not be easy,” Pogba noted.

“There are no small teams or bad players in a World Cup, but the road is still long, we have to fight and be very strong.”

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Dr David Margolis, ViiV Healthcare, USA

An injectable antiretroviral therapy (ART) consisting of two drugs (cabotegravir and rilpivirine) administered every four or eight weeks may be as effective as a daily oral dose of the drugs in maintaining viral suppression in patients with HIV, according to a new phase 2 trial published in The Lancet.

In the study, patients were given injectable ART as a maintenance therapy over 96 weeks once they had achieved viral suppression after 20 weeks of daily oral medication.

In Uganda many patients have complained of not being comfortable in swallowing the ARV drugs with some reports indicating some patients abandon treatment along the way.

However, reports suggest that the potential for a long-acting injectable ART could ease the burden faced by people living with HIV of having to take daily oral medication lifelong to manage the disease. Phase 3 trials are ongoing and are needed to confirm the results, and further trials will be needed in wider groups of patients to generalise the findings.

The trial is presented at the International AIDS Society meeting in Paris, France.

An estimated 36.7 million people worldwide are living with HIV, and advances in ART have led to improved survival and quality of life for people with HIV. However, current treatment requires taking a daily dose of medication lifelong, and poor compliance can result in treatment failure or the emergence of drug-resistant mutations. Long-acting injectable drugs potentially offer a more convenient way of managing the disease.

“Adherence to medication remains an important challenge in HIV treatment. Long-acting injectable ART could provide some patients with a more convenient approach to manage HIV infection that avoids daily oral dosing, and the need to keep, store, and transport medications as they go about their daily lives,” explains author of the LATTE-2 study Dr David Margolis, ViiV Healthcare, USA.

“The introduction of single tablet medication represented a leap forward in ART dosing, and long-acting antiretroviral injections may represent the next revolution in HIV therapy by providing an option that circumvents the burden of daily dosing. The results through to 96 weeks with this two-drug regimen are encouraging, and we now need further research, including the ongoing phase 3 trial, to confirm these findings,” Dr Margolis adds.

HIV injectable drugs

According to the report, the  trial began with an induction phase in order to identify any potential adverse events to the drugs before administering a long-acting injectable. 309 participants were included in the initial induction phase of the trial, during which they were given daily oral doses of cabotegravir (30mg) and abacavir-lamivudine (600mg-300mg) over 20 weeks.

The majority of participants tolerated the drugs and reached viral suppression (plasma HIV-1 RNA less than 50 copies per mL) and was therefore eligible to enter the maintenance phase.

286 participants were included in the maintenance phase, where they were randomly assigned to receive injectable cabotegravir plus rilpivirine at 4-week intervals (115 patients), at 8-week intervals (115 patients) or continue on the daily oral dose of cabotegravir and abacavir-lamivudine (56 patients).

32 weeks after randomisation, viral suppression was maintained in 91% (51/56) of patients in the oral medication group, 94% (108/115) in the 4-week group, and 95% (109/115) in the 8-week group.

At 96 weeks, viral suppression was maintained in 84% (47/56) of patients in the oral medication group, 87% (100/115) in the 4-week group, and 94% (108/115) in the 8-week group.

Pain at the site of the injection was the most commonly reported adverse event (97% of patients in the 4-week group, and 96% in the 8-week group). Most reactions were mild or moderate and lasted an average of 3 days. In total, 2 of 230 (<1%) patients receiving the injectable two-drug regimen discontinued due to injection intolerance.

Other adverse events reported included nasopharyngitis, diarrhoea, and headache, and rates were similar in all three groups. A total of 11 patients (4%) developed an adverse event during the maintenance phase which led to withdrawal from the study: 8 patients (7%) in the 4-week group, two (2%) in the 8-week group, and one (2%) in the oral treatment group. Two deaths occurred during the study: one from a motor vehicle accident, and the other following an epileptic seizure which was not thought to be due to the treatment.

The trial was done at 50 sites in the USA, Germany, Canada, Spain, France and Germany. Although it included patients from five countries, most (91%) of the participants were male. Also, participants were only eligible for the trial if they had a CD4+ cell count of at least 200 cells per mm3, which does not necessarily represent the global population living with HIV. Further research in more diverse groups of patients is now needed.

Professor Joe Eron, University of North Carolina at Chapel Hill, USA, author of the study, says: “The results of LATTE-2 show that a long-acting injectable antiretroviral regimen has the potential to be both highly effective and well tolerated over a long period of time. These data provide a strong foundation for the ongoing and planned phase 3 trials which will hopefully lead to an effective, well tolerated alternative to daily antiretroviral therapy.”

Writing in a linked Comment, Professor Mark A. Boyd, University of Adelaide, Adelaide, Australia, and Professor David A. Cooper from the Kirby Institute, University of New South Wales, Sydney, Australia, say:

“While injectable ART might be attractive for some or perhaps many people living with HIV (….), there will inevitably be a trade-off between the convenience of not having to adhere to oral therapy and the inconvenience and discomfort associated with injectable long-acting ART. It is possible that injectable ART will be more attractive the less one must be injected. This is particularly the case in the current era when oral therapy is administered as one pill, once daily, and (at least in Australia) people living with HIV can be dispensed anywhere from 2 to 6 months’ supply of ART at a time. This scenario, compared with having to seek health care to be injected on a monthly basis, might make the injectable option seem less convenient than conventional oral therapy for some people. This is compounded by the fact that health-care systems are generally not configured to facilitate regular, recurrent injections in a timely and convenient way to people who are well. Changing this will take innovation, political will, and time.”

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Study Subject(s): IFA is offering scholarships for MBA in Luxury Brand Management and Global Fashion Media.
Course Level: This scholarship is available to pursue postgraduate degree.
Scholarship Provider: International Fashion Academy
Scholarship can be taken at: The students have to spend some weeks in France (Paris) and some in China (Shanghai)

Eligibility: Requirements:
– Bachelor graduates, preference will be given to candidates with background in business administration, marketing, media & mommunication and fashion design related field
– Past transcript from university education
– IELTS of above 7.0 (Native English speakers do not need to provide)
– At least 3 years of relevant working experiences.
–both domestic and international students are eligible to apply.

Scholarship Open for International Students: Both domestic and international students are eligible to apply.

Scholarship Description: International Fashion Academy (IFA Paris), a leading fashion and luxury education provider with campuses in Paris and Shanghai, is pleased to announce their scholarship scheme for the 2013-2014 academic years.  IFA will award over €300,000 to students through a combination of full and partial scholarships at both the postgraduate and undergraduate levels.  At the postgraduate level, IFA will award a total of 10 scholarships to students to pursue their MBA Luxury Brand Management and MBA Global Fashion Media.  The latter is an exciting new course that will be launched in 2013.  Both courses take advantage of IFA’s unique dual campus structure, and split their academic year between Paris and Shanghai. Graduates of such courses are in high demand among industry leaders, and experiencing China and its consumers is now an asset when looking for a job back home.

Number of awards offered: In 2013, IFA is pleased to offer 10 scholarships at the Postgraduate level.

Duration of award(s): 24 weeks in Shanghai + 12 weeks in Paris (MBA Luxury Brand Management) and 24 weeks in Paris + 12weeks in Shanghai (MBA Global Fashion Media).

What does it cover?
–MBA Luxury Brand Management (24 weeks in Shanghai + 12 weeks in Paris)
2 x full scholarship, worth  €14,800
3 x half scholarship, worth   €7,400
-MBA Global Fashion Media (24 weeks in Paris + 12weeks in Shanghai)
-2 x full scholarship, worth  €13,800
-3 x half scholarship, worth €6,900
The scholarship includes tuition fee only.

How to Apply: To get started and receive a scholarship application package, please contact us at scholarship@ifaparis.com with your full name and course title.

Scholarship Application Deadline: Applications are to be submitted in full by April 2, 2013 at the latest for admission in the fall semester.

Further Scholarship Information and Application

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Postgraduate Scholarships in France: From year to year, the French Embassy in Kenya strengthens its scholarship attribution policy. Around 10 scholarships are allocated annually.

These scholarships are mainly intended for postgraduates who are already engaged in a professional activity and want to develop their academic qualifications in agreement with their employer and with the support of French scientific networks.

Sandwich Doctoral Scholarship

The scholarship finances 3 stays of 3 months each in France, and a fourth stay of a couple of weeks intended for the defence, over a 3 to 4 year period.

Acceptances of the following stays are subject to achievement of scientific targets set by the scholarship holder in collaboration with his/her supervisor.

The scholarships cover travel and living expenses, registration fees in the university and health insurance.

Scholarship Eligibility Criteria:

• Kenyan citizen
• A master’s degree holder
• French host institution identified
• Employer’s agreement or financial plan about the doctoral training
• Age limit: 45 years for staff of higher education and research institutions; 30 years for students.

Master Scholarship:

The scholarships cover travelling and living expenses, registration fees in the university and health insurance over the whole training period in France (maximum 12 months).

Scholarship Eligibility Criteria:

• Kenyan citizen
• A bachelor’s degree holder
• French study programme identified
• Staff of national high education and research institutions or French enterprises based in Kenya
• Employer’s agreement or co-funding plan from the French company
• Age limit: 40 years.

For more information and scholarship applications, see: Postgraduate Scholarships in France

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The Uganda Broadcasting Corporation (UBC) has finally bowed down to public requests and criticism and switched on most of the radio stations it had switched off on January 8^th this year over non payment of transmission bills amounting to three billion Uganda shillings.

The radios UBC switched off included BBC radio, Radio France International, Suubi FM, Buddu Radio, Voice of Africa, Greater Africa Radio, Bilal FM, and Italian Embassy Security Communication system.

Other communication houses UBC switched off also included Itel, Tangerine, Citizen TV, and infocom. Sources in UBC have told our reporters that most of the affected stations like TOP radio, radio Buddu among others were allowed to operate because they paid their electricity bills and others have entered into agreements with UBC.

Acting managing director of UBC, Paul Kihika says that UBC doesn’t have any problem with radio stations that meet all necessary requirements.

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Amb. Escure replaces Mr. Jacques Champagne de Labriolle whose tour of duty as France’s Ambassador to the United Republic of Tanzania ended late last year.

In a letter dated 21 November 2011, France’s Minister of Foreign and European Affairs, Mr. Alain Juppe states that H.E. Mr. Marcel Escure’s mission to the EAC will further strengthen the ties between France and the East African Community.

“France wishes to support the integration process that your Community has started as well as the rapprochement initiated with the Southern African Development Community and the Common Market for Eastern and Southern Africa,” noted the French Foreign Minister.

The EAC Secretary General Amb. Sezibera hailed the cordial relations that exist between France and the EAC Partner States, and briefed the French envoy on the critical activities that will dominate the integration agenda in the next five years which include consolidation of the EAC Customs Union and establishing a single customs territory; implementation of the provisions of the Common Market Protocol and; conclusion of the Protocol for the Establishment of the East African Monetary Union.

For more information please contact: Owora Richard Othieno, Head of Department; Corporate Communications and Public Affairs; Tel: 255-768-835021; Email: othieno@eachq.org

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