Contributory or predisposing factors of kidney infections: Diseases or conditions that cause stasis of urine in the urinary tract promote multiplication of organisms in the urinary tract and ascension of infection.

Diseases that impair immunity promote multiplication of organisms in the urinary tract and ascension of infection. Presence of a device in the urinary tract promotes multiplication of organisms in the urinary tract and ascension of infection
1-Obstructions to urine flow: Vesicoureteric reflux (VUR) is the most important predisposing factor in children younger than 6 years. Obstruction of outflow of bladder: benign prostatic hypertrophy, prostatic carcinoma, bladder tumors.

Carcinoma arising from renal tract, for example, renal cell carcinoma, bladder cancer, ureteric tumors; carcinoma arising outside renal tract and impinging on it, for example, bowel, cervix, prostate…Radiotherapy or surgical damage to ureters, pregnancy encourages reflux by dilatation of the ureters and probably reduces immunity of renal parenchyma, calculi cause obstruction and stasis, and act as foci for infection, neurologic abnormalities, for example, spina bifida, multiple sclerosis, polycystic kidney disease, affects 0.8/1000 of the population and is inherited as an autosomal dominant trait and renal parenchymal damage due to tuberculosis.

Ends